A drug-induced disease is the unintended effect of a drug that results in mortality or morbidity with symptoms sufficient to prompt a patient to seek medical attention and/or to require hospitalization. Since the publication of the first edition of this book in 2005, numerous drugs have been withdrawn from the market in the United States because of morbidity and/or mortality associated with drug-induced disease. Despite best efforts to ensure the safety and effectiveness of all drugs, millions of patients each year develop drug-induced diseases. Every time a patient presents with a new disease or an exacerbation of an existing condition, the clinician should ask, “Could this be drug-related?”

Now in its second edition, this essential and comprehensive resource provides a detailed analysis of how to prevent, identify, and manage drug-induced diseases.

Features include:

• Chapters devoted to more than 50 disease states
• In-depth tables, including coverage of drugs implicated in drug-induced diseases, epidemiology, mechanisms, signs and symptoms, risk factors, prevention, and management
• New chapters on “Drug Safety and Drug-Induced Diseases: The Legal, Regulatory, and Practice Environment” and “Evaluating Patients for Drug-Induced Diseases”
• Levels of Evidence classification for identifying the strength of evidence that links a listed drug to a specific drug-induced disease