Chapter: Acute Management of Prescription and Non-Prescription Drug Overdoses

1. Classify prescription drug overdose by patient presentations.
2. Evaluate the causative agents of a drug overdose based on history and clinical findings of presentation.
3. Develop a treatment paradigm that may be applied in all prescription drug overdoses.
4. Assess the relevance of each therapeutic target in drug overdose in a specific drug overdose scenario.
5. Devise a plan for treatment of anticholinergic, sodium channel blocker, tricyclic antidepressant, bupropion, digoxin, sulfonylurea, alpha-2 agonist, iron, valproic acid, clonidine, and salicylate overdose.
6. Justify the use of specific antidotes in overdose. 

Chapter: Management of Alcohol Withdrawal

1. Assess factors contributing to alcohol withdrawal in patients.
2. Evaluate the risk of alcohol withdrawal and severity of symptoms.
3. Design an appropriate benzodiazepine or phenobarbital therapy plan for patients with alcohol withdrawal syndrome.
4. Justify the role of adjunctive therapies in patients with alcohol withdrawal based on patientspecific criteria.
5. Develop a plan for the management of patients with complicated alcohol withdrawal symptoms (seizures, delirium, and resistant alcohol withdrawal). 

Chapter: Acute Management of Fluid and Electrolyte Disorders

1. Evaluate the efficacy and safety of different fluid types in critically ill patient populations.
2. Develop recommendations for fluid resuscitation for patients with sepsis and liver failure.
3. Analyze characteristics of patients with electrolyte disorders to determine the most likely etiology.
4. Assess patients for common drug-related causes of electrolyte disorders.
5. Design medication therapy plans for the treatment of hypernatremia, hyponatremia, hyperkalemia, and hypercalcemia based on the underlying etiology. 

Chapter: Perioperative Management of Patients in the ICU

1. Design a pain management plan for a patient in the surgical ICU (SICU).
2. Apply knowledge of shock types and markers of resuscitation to develop a postoperative resuscitation and hemodynamic management plan.
3. Develop a plan for the prevention of common SICU complications.
4. Develop a plan for the management of hematologic disorders of bleeding and prevention of thromboembolism for a SICU patient.
5. Evaluate the anti-microbial regimen of a SICU patient for appropriateness with regard to site of infection, common pathogens, and duration of therapy.
6. Justify appropriate blood glucose goals and convert a continuous insulin infusion for the management of stress hyperglycemia to an appropriate basal-bolus regimen in a SICU patient. 

Chapter: Acute Arrhythmias

1. Assess patients for risk factors for ventricular arrhythmias.
2. Develop a pharmacologic plan to restore spontaneous circulation and maintain end-organ perfusion during cardiac arrest.
3. Design an antiarrhythmic medication regimen to suppress ventricular arrhythmias and implantable cardioverter-defibrillator shocks.
4. Modify pharmacologic therapy to mitigate the risk of QT interval prolongation and torsades de pointes.
5. Develop appropriate therapy for a patient with supraventricular tachycardia and bradyarrhythmias. 

Chapter: Acute Agitation, Delirium, and Sleep Management

1. Apply bedside clinical assessment tools to detect pain, agitation, and delirium in the critically ill patient.
2. Design an evidence-based pharmacotherapy regimen for agitation in the critically ill patient.
3. Evaluate pharmacologic approaches for prevention and management of ICU delirium.
4. Assess therapeutic approaches to improve sleep quality in critically ill patients.
5. Develop a population-based approach for agitation, delirium, and sleep disturbance management in the ICU.  

Interactive Case: Life-threatening Bleeding Caused by Anticoagulants

1. Classify antithrombotic agents according to labeled indication, mechanism of action, and pharmacokinetic properties.
2. Assess life-threatening bleeding events caused by antithrombotic agents for reversal.
3. Evaluate the risk-benefit of treatments for life-threatening bleeding in the setting of an antithrombotic agent.
4. Develop an appropriate drug-dose regimen for a patient with life-threatening bleeding caused by an antithrombotic agent. 

Interactive Case: Rapid Sequence Intubation

1. Assess the pharmacologic properties and indication or pretreatment agents used in rapid sequence intubation (RSI).
2. Evaluate the pharmacologic properties of induction agents used in RSI.
3. Distinguish the pharmacologic properties of neuromuscular blocking agents used in RSI.
4. Design appropriate patient-specific RSI regimens, and incorporate patient disease state interactions into them.