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PSAP in JACCP - Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia and Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research - 2022 March


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Faculty Information

PSAP in JACCP features are developed from activities presented as part of the Pharmacotherapy Self-Assessment Program (PSAP).

Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia

This feature was developed from an interactive case presented in PSAP 2021 Book 2 (Neurology and Psychiatry).

  • Interactive Case: Click here to access the interactive case.
Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research

This feature was developed from an interactive case appearing in PSAP 2021 Book 2 (Neurology and Psychiatry).

  • Interactive case: Click here to access the interactive case.

Author - Reviewer Information

Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia

Author: Barbara Farrell, Pharm.D., ACPR, FCSHP
Reviewed by: Kristina M. Ward, Pharm.D., BCPS, BCPP; and Amanda McFee Winans, Pharm.D., BCPS, CACP

Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research

Author: David R. Foster, Pharm.D., FCCP; and Kevin M. Sowinski, Pharm.D., FCCP
Reviewed by: Curtis E. Haas, Pharm.D., FCCP; Micheline Goldwire, Pharm.D., MS, BS, BCPS; and Tanvi Patil, Pharm.D., BCPS

Target Audience and Learning Objectives

Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia

Target audience for this application-based activity:
Pharmacotherapy specialists and advanced level clinical pharmacists encountering patients with psychiatric and neurologic diseases.

Learning Objectives

  1. Evaluate patients with insomnia for appropriateness of benzodiazepine receptor agonist (BZRA) deprescribing.
  2. Apply patient engagement and shared decision-making approaches to facilitate BZRA deprescribing.
  3. Design, implement, and monitor BZRA deprescribing plans for patients with insomnia.
  4. Develop nonpharmacologic support plans for insomnia during and after BZRA deprescribing.
Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research

Target audience for this application-based activity:
Pharmacotherapy specialists and advanced-level clinical pharmacists who regularly design research studies or who are called upon to interpret the results of published data.

Learning Objectives

  1. Evaluate appropriate clinical trial study design elements, including considerations of randomization and blinding.
  2. Distinguish clinical trial design features including subgroup analyses, composite endpoints, early cessation, surrogate endpoints, non-randomized designs, and internal/external validity.
  3. Assess event rates or risks observed in clinical trials.
  4. Compute and evaluate absolute risk reduction, relative risk reduction and number needed to treat.
  5. Identify decision errors (Type I, Type II error) encountered in clinical trials.
  6. Justify the use of components necessary for sample size estimation in clinical trials.

Disclosure of Potential Conflicts of Interest

Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia

Barbara Farrell: Grants (CABHI Spark Program; Government of Ontario through the Bruyere Centre for Learning, Research and Innovation in Long-term Care; Canadian Institutes of Health Research; Canadian Foundation for Healthcare Improvement and Canadian Frailty Network; The Ottawa Hospital Academic Medical Organization); Honoraria (Pacific Psychopharmacology Conference, Canada; Ontario Long-Term Care Clinicians, Canada; The University of Bath; ASHP; National University Hospital, Singapore; Peterborough Regional Health Centre; Copenhagen University Hospital Bispebjerg; Canadian Foundation for Healthcare Improvement; Canadian Society of Hospital Pharmacists)
Kristina M. Ward: Honoraria (College of Psychiatric and Neurologic Pharmacists; ASHP)
Amanda McFee Winans: Nothing to disclose

Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research

David R. Foster, Kevin M. Sowinski, and Tanvi Patil: Nothing to disclose
Curtis E. Haas: Consultancies (Vizient, KJT Consulting, Pharmacy Times)
Micheline Goldwire: Honoraria (Alliance for Pharmacy Compounding)

Continuing Pharmacy Education and Recertification Instructions

Available CPE/Recertification credits: Anyone who purchases, successfully completes and passes the required posttests for this feature can earn up to 3.0 contact hours of CPE/Recertification credit.

Part I: Interactive Case: Rational Deprescribing of Benzodiazepine Receptor Agonists for Insomnia

Universal Activity Number: 0217-0000-22-017-H01-P
1.5 CPE contact hours
Application-Based Activity

Part II: Statistics in Practice: Study Design and Application of Inferential Statistics – Interventional Research

Universal Activity Number: 0217-0000-22-018-H04-P
1.5 CPE contact hours
Application-Based Activity

Release date: March 8, 2022
BCPS posttest submission deadline: 11:59 p.m. (Central) on September 8, 2022.
ACPE posttest submission deadline: 11:59 p.m. (Central) on March 8, 2025.

TO EARN CPE/RECERTIFICATION CREDIT FROM THIS FEATURE
Posttest access: Purchase the required posttests (see below); then go to www.accp.com and sign in with your e-mail address and password. PSAP in JACCP features are listed under My Products on your My Account page.
Technical support is available from 8 a.m. to 5 p.m. (Central) weekdays by e-mail at [email protected].

Release Date: March 08, 2022
BCPS Deadline: September 08, 2022
ACPE Deadline: March 08, 2025

Format: Online Test

CPE Credit

The American College of Clinical Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

The American College of Clinical Pharmacy is approved by BPS as a provider for the recertification of BCPS.

BPS is an autonomous division of the American Pharmacists Association. To maintain its strict, independent standards for certification, BPS does NOT endorse or provide review information, preparatory courses, or study guides for board certification examinations. BPS, through its specialty councils, is responsible for specialty examination content, administration, scoring, and all other aspects of its certification programs. BPS is totally separate and distinct from ACCP. For information about BPS specialty recertification the BPS recertification process, go to: www.bpsweb.org/

To receive recertification credit, posttests must be submitted prior to the recertification posttest deadline (see above). Only completed tests are eligible for credit; no partial or incomplete tests will be processed. You may complete one or all available posttests for credit.

The passing point to earn recertification credit is based on an expert analysis of the assessment items in each posttest. Any posttest submitted before the recertification test deadline that meets this passing point will earn recertification credits. These credits will be assigned as of the date of test submission and reported within 48 hours to BPS. For statements of recertification credit, visit www.bpsweb.org.

In accordance with BPS guidelines concerning remediation for products launched in 2024 and after, posttests that do not reach the passing point for recertification credit will generate a second-chance test option. This test will automatically appear in the learner’s My Account page and will have assessment items presented in a different order. To qualify for recertification credit, the second-chance test must be submitted before the recertification deadline stated above.

The ACCP Recertification Dashboard is a free online tool that can track recertification credits as they are earned through ACCP and schedule new opportunities for credits from upcoming ACCP professional development programs. Questions regarding the number of hours required for recertification should be directed to BPS at www.bpsweb.org.


Commercial Support

The American College of Clinical Pharmacy does not solicit or accept external commercial/financial support for its continuing pharmacy education activities. No commercial/financial support has been solicited or accepted for this activity.