Scientific Poster Session IV - Original Research

Original Research
  Tuesday, November 14, 2023
  08:30 AM–10:00 AM

Abstract

Introduction: The promise of pharmacogenomics (PGx) to improve medication safety and effectiveness is consistently demonstrated in the literature, ushering in the early majority of adopters. Successful uptake hinges on clinicians involved in patient care. Surveys of primary care providers found most lack formal training in PGx and are unprepared to utilize it. The relevance of PGx extends beyond primary care, so there is a need to assess prescriber preparedness across relevant specialties as PGx programs expand. As the profession leading PGx implementation, it's important for pharmacists to recognize where their expertise can supplement their physician and advanced practice provider colleagues.

Research Question or Hypothesis: What's the experience and perception of pharmacogenomics for prescribers across eleven specialties at an integrated academic health system?

Study Design: This is a cross-sectional, quantitative online survey.

Methods: A link to the survey was emailed to physicians and advanced practice providers at an integrated, academic health system in Rhode Island and practicing in one of eleven relevant specialties. Survey format included multiple choice, Likert-type, and Likert scale questions on respondent demographics, education on PGx, utilization of PGx, comfort with PGx, and beliefs on PGx utility.

Results: The response rate was 3.7% (60/1614) and represented eight specialties. Majority were physicians (70%) and had been practicing for either 20+ years (32%) or were currently a trainee (22%). Over 70% had no education in PGx but 77% were interested in receiving some. The mean PGx comfort score was 10 out of a possible 40. 85% agreed genetics can influence response to medications and 53% agreed they prescribe medications influenced by PGx. When asked if their patients would benefit from PGx, 22% agreed and 55% were neutral.

Conclusion: Almost all respondents had little to no experience with PGx, but were willing to learn more. There is significant opportunity to improve prescribers’ comfort with using PGx in practice.

Presenting Author

Lauren Lemke PharmD
Lifespan

Authors