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Mon-113 - Retrospective Assessment of Modifiable and Non-modifiable Patient Specific Factors that Contribute to Surgical Site Infections

Scientific Poster Session III: Students Research-in-Progress

Students Research in Progress
  Monday, November 13, 2023
  01:00 PM–02:30 PM

Abstract

Introduction: Surgical site infections (SSI) can be prevented if appropriate strategies are implemented. Surgical antimicrobial prophylaxis is dependent on procedure type, duration of operation, historical colonization and cultures.1 Surgical patients are at a higher risk for infection if the type of antibiotic chosen is inappropriate for the organisms suspected at the surgical site, administration of the presurgical dose is outside the accepted 1-hour window, and if repeat doses are not administered when clinically appropraite.1 It is known that patient specific factors including uncontrolled blood sugars, history of smoking, recent infection, immunocompromising conditions, and high dose steroid use in the preoperative period can contribute to poor wound healing and increase the risk of infection.1 Management of these risk factors provides opportunity for pharmacist intervention in the perioperative period.

Research Question or Hypothesis: Did inappropriate management of patient specific risk factors during the preoperative and perioperative period contribute to surgical site infection?

Study Design: Retrospective, Chart Review

Methods: Patients from March 1, 2020 to Mach 31, 2023 who had a reportable SSI at the facility were aggregated for a retrospective chart review. Patients were then stratified based on which surgical intervention was performed (orthopedic, neuro, obstetrics, etc.) to assess infections occurring in similar surgical interventions. Data was collected for each patient including: infectious organism(s), resistance, timing and type of antibiotics, existing colonization, previous infections, vital signs, glycemic control, medications, and smoking status.

Results: Data collection will be complete for patients (n=97) and reported as descriptive statistics for the following categories: immunocompromise, antibiotic appropriateness, glycemic control, steroid use, and smoking status, transfusions, and anticoagulation.

Conclusion: Final conclusions will be presented at the 2023 ACCP Annual Meeting, Dallas, Texas.

Resources: Seidelman JL, Mantyh CR, Anderson DJ. Surgical Site Infection Prevention: A Review. JAMA. 2023;329(3):244–252.

Presenting Author

Kylar Crouse BSPS
Aurora BayCare Medical Center

Authors

Dustin Carneal Pharm.D