Residents and Fellows Research in Progress
Monday, November 13, 2023
01:00 PM–02:30 PM
Abstract
Introduction:
Pharmacogenomics (PGx) holds potential to transform patient care through personalized treatment approaches. The introduction of a pharmacist-led PGx service within a family medicine training clinic aimed to promote individualized treatments and leverage pharmacists' knowledge in identifying medication therapy problems (MTPs) and providing PGx-guided recommendations.
Research Question or Hypothesis: Develop and evaluate PGx integration in family medicine training, with emphasis on psychotropic and chronic pain therapies.
Study Design: Hybrid, pilot study
Methods: A pharmacist-led PGx program was developed and implemented, covering testing, patient identification, referral processes, pharmacist workflow, clinical education, and communication of testing procedures and results. The primary outcome was to determine the number of patients who completed the PGx consultation process, which involved two sessions (initial visit and follow-up visit). Secondary outcomes included patient referral patterns, identification of MTPs, recommendations based on gene-drug pairs, and subsequent clinical actions taken. Descriptive statistics were used to analyze and interpret the data.
Results: Between October 12, 2022 and June 22, 2023, 13 patients were referred for PGx testing by nine providers. Eleven (85%) patients completed the initial PGx visit, and eight (62%) underwent the full consultation process. Four (31%) patients faced barriers to completing testing, such as cost or third-party vendor requirements. At the time of submission, one patient was awaiting the second visit to discuss their results. Twenty MTPs were identified and resolved using PGx guidance. Thirteen (65%) MTPs focused on preventing adverse medication events through preemptive testing and patient education on potential risks based on genetic results.
Conclusion: A pharmacist-led PGx service with an emphasis on psychotropic and chronic pain conditions was developed and successfully implemented into a family medicine residency training clinic. This pilot serves as a model to extend this service to a broader range of patients and across various types of interprofessional settings.
Presenting Author
Erika Harvey PharmDUniversity of Minnesota
Authors
Jody Lounsbery PharmD, BCPS
University of Minnesota College of Pharmacy Department of Pharmaceutical Care & Health Systems
Jean Moon Pharm.D., BCACP
University of Minnesota College of Pharmacy