Scientific Poster Session II: Students Research-in-Progress

Students Research in Progress
  Sunday, November 12, 2023
  12:45 PM–02:15 PM

Abstract

Introduction: Empiric antibiotic therapy has served as a cornerstone of treatment utilized in sepsis, pneumonia, and urinary tract infection protocols. Data suggests that appropriate empiric antibiotic therapy can have positive influences in patient outcomes, if initiated in a timely manner. Delays in antimicrobial therapy have been correlated with increased mortality in previous studies. With worldwide increases in the incidence rates of multidrug resistant (MDR) Pseudomonas aeruginosa strains, inappropriate antimicrobial therapy and delays in subsequent dosing could result in the progression towards MDR Pseudomonas aeruginosa. We aim to study whether a correlation exists amongst delayed anti-pseudomonal antibiotic administration.

Research Question or Hypothesis: The purpose of this study is to evaluate the appropriate timing of second-dose anti-pseudomonal antibiotic administration in the emergency department (ED) at University Medical Center of New Orleans (UMCNO).

Study Design: Retrospective Chart Review

Methods: This is an IRB-approved retrospective chart review conducted at University Medical Center New Orleans (UMCNO) evaluating the appropriate timing of second-dose anti-pseudomonal antibiotic administration in the emergency department from June 1, 2022, through June 1, 2023. The primary outcome was to evaluate time to administration of the second dose for anti-pseudomonal coverage. Secondarily, we aimed to evaluate the time to first dose and appropriateness of antimicrobial agent selection as indicated by institutional and national guidelines. This study included patients 18 years of age and older at the time of arrival to the emergency department who received an anti-pseudomonal antibiotic and were subsequently admitted to the hospital. Antibiotic selection, indication, dose, frequency and duration were collected from the electronic medical record.

Results: Full results to be presented.

Conclusion: Full results to be presented.

Presenting Author

Timothy Roberts PharmD Candidate
University of Louisiana Monroe

Authors

Gabriela Andonie PharmD
University of Louisiana Monroe College of Pharmacy

Jennifer Hoh PharmD
University of Louisiana Monroe College of Pharmacy