Across the globe, health disparities exist among indigenous and remote populations, especially for non-communicable diseases (NCDs). NCD management is complex and requires effective systems to ensure appropriate detection, management, and follow-up. However, these systems are often constrained in increasingly remote areas, and are worsened when intersected with other measures of marginalization. Pharmacists are in a unique position to contribute to the development of improved health systems and ensure equitable and just access to health care for all people. This special session will focus on understanding the structural factors underlying health inequities in remote areas globally for indigenous populations and then provide examples of effective strategies for improving NCD management in rural settings globally.