This session will focus on management of several toxicological emergencies encountered in the Emergency Department (ED). A needs assessment survey was performed and the following topics were considered: drugs we love and or hate in practice, stroke care updates, toxicological emergencies, anticoagulation reversal strategies, acute alcohol withdrawal and novel agents, rapid administration of antiepileptic drugs to patients in the ED, and ways to reduce patient return to the ED. Based on the results of the survey, the PRN felt that the management of toxicological emergencies would be the preferred topic for this year's focus session. We are planning a 2-part presentation. The first section will be a debating of Anavip vs Crofab in the role of snake envenomations and discussing the variable regimens and routes of administration of acetylcysteine for acetaminophen overdose and the settings in which they would be optimal. These presentations will involve case studies to drive home key points and address the challenges (formulary agent choice based on likely envenomations, dose rounding, ect) that pharmacists face with high-cost antidotes as well as patient focused decisions with regards to their disposition in the setting of potential transitions of care and the most cost effective N-acetylcysteine formulations based on their presentation and underlying disease severity. The target audience for this session is emergency medicine practitioners as well as practitioners in other acute settings such as the intensive care unit, and students/residents interested in emergency medicine. The purpose of this session will be to provide clinicians with the tools and strategies necessary to manage these toxicological emergencies.