American College of Clinical Pharmacy
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  Poster Hall

Sun-23 - Pharmacist-led interventions for disease management and risk reduction in patients with Ischemic Heart Disease: a non-randomized controlled trial

Scientific Poster Session II - Original Research

Original Research
  Sunday, October 13, 2024
  12:45 PM–02:15 PM

Abstract

Introduction:

Pharmacist-led interventions have been identified as a valuable component in the management of ischemic heart disease (IHD), aiming to improve patient outcomes and reduce risks associated with the disease. Contradictory to the general optimism about pharmacist-led interventions, there is a noted gap in robust evidence demonstrating their impact on clinical or humanistic outcomes.

Research Question or Hypothesis:

The study aimed to determine the impact of pharmacist-led interventions for disease and risk management in patients with IHD.

Study Design:

Interventional non-randomized clinical trial.

Methods:

The study protocols are registered in the Australian New Zealand registry (Registration # ACTRN12622000996763). The European Quality of Life questionnaire – 5 dimensions - 3 levels EQ-5D-3L questionnaire (Reference no. 62143) was used for determination of post-intervention impact on patients with IHD. The independent t-test, MANOVA and principal component analysis (PCA) models were used to analyze the data. The data was estimated using a 95% confidence interval (CI).

Results:

For individuals with IHD, the Levene's test values for equality of variances (F) on the impact on their psychological well-being, social relations, general health, physical health, problems faced, and overall quality of life were 14.071, 164.610, 119.208, 523.523, 346.899 and 226.355 while t value of t-test for equality of means for these factors were -19.018, -37.262, -9.804, -50.598, -39.242 and -22.280. The MNOVA (F values) were [F (1388.447, 96.118, 2560.166, 361.672, 1539.963, and 496.414 respectively. PCA revealed 62% of the analysis’s variation for six components. The p-value for all these factors was 0.000.

Conclusion:

The results of the study demonstrated that the interventions led by pharmacists had noteworthy effects on managing the disease and reducing the risk in patients with ischemic heart disease, resulting in enhancements in overall quality of life, as well as general, psychological, and social health of patients.

Presenting Author

Amjad Khan PhD
Xi'an Jiaotong University

Authors

Yu Fang PhD
Xi'an Jiaotong University

Umm-e- Kalsoom M.Phil.