Scientific Poster Session I - Original Research

Original Research
  Saturday, October 12, 2024
  11:30 AM–01:00 PM

Abstract

Introduction: Total overdose deaths rose by 60% between 2019 and 2021. Medications for opioid use disorder (MOUD) have been associated with reduced overdoses and opioid-related hospitalizations. Involvement of addiction medicine consult services (AMCS) in patient care have been shown to reduce all-cause 90-day mortality post-discharge. This study aimed to expand on the of AMCS on initiation of MOUD in hospitalized patients.

Research Question or Hypothesis: Does access to an AMCS increase MOUD initiation in inpatients with untreated OUD?

Study Design: This is a retrospective, quantitative, cohort study.

Methods: Site 1 developed an AMCS in 2021, while site 2 has no AMCS. Data on MOUD initiation and demographics were collected as a baseline. Another set of data for each site was collected for a period after development of an AMCS at site 1. We compared the change in MOUD initiation rates between these periods at site 1 to site 2. The primary objective was to assess how an AMCS influences MOUD initiation in patients with untreated OUD.

Adults aged 18 or older with ICD-10 codes related to OUD not currently receiving treatment were included. Patients with an active cancer diagnosis were excluded.

Z-Tests for proportions were used to estimate and test the difference in rates of MOUD within each site. Multiple logistic regression was used to estimate the slope of change in the MOUD rate.

Results: 504 patients were assessed. Rate of MOUD initiation for site 1 was 8% (10/126) for the baseline and 21% (26/126) for post-period (difference in proportions = 0.2; 95% CI 0.04-0.21; p=0.004). Rate initiation for site 2 was 5% (6/126) for the pre-period and 6% (8/126) for the post-period (difference in proportions = 0.016; 95% CI -0.04-0.75; p=0.582).

Conclusion: Availability of a hospital AMCS increased MOUD initiation in patients with a history of OUD.

Presenting Author

Madeline Dillen PharmD
UPMC St. Margaret

Authors

Megan Baumgartner PharmD, BCPS
UPMC St. Margaret

Frank D'Amico PhD
UPMC St. Margaret

Sanketh Proddutur MD
UPMC St. Margaret

Joshua Shulman MD
UPMC Shadyside

Alexandria Taylor PharmD, BCPS
UPMC St. Margaret