Residents and Fellows Research in Progress
Saturday, October 12, 2024
11:30 AM–01:00 PM
Abstract
Introduction:
Recent studies indicate benefits of OPAT include shorter hospital stays, decreased costs, and improved patient quality of life. This study's purpose was to show the clinical impact of an OPAT program on patients being discharged on IV antimicrobials.
Research Question or Hypothesis: Identify the impact of a pilot OPAT program on time to re-admission and treatment success rate at completion of therapy.
Study Design: This is an IRB approved retrospective chart review of adult patients admitted between January 1st to December 31st, 2023. Inclusion criteria was patients age >18 years of age who were discharged on intravenous antimicrobials for >7 days of therapy remaining at the time of discharge. Participants were excluded if they received OPAT without an ID consult or were transferred to a different acute care facility.
Methods: The primary outcome of the study was to evaluate the impact of OPAT program on 30 and 90 day readmission as well as OPAT related readmission. Secondary outcomes were the treatment success rate at completion of therapy and compliance of outpatient ID follow up.
Results: A total of 173 patients were included in the final analysis with 82 patients in the pre-intervention group (PRIG) and 91 patients in the post intervention group (POIG). Patients in POIG were less likely to experience OPAT related readmissions (31.7% vs 16.5%, P=0.02). There was no difference in all-cause, 30 and 90 re-admission between groups. There were trends towards higher treatment success with POIG compared to PRIG (67% vs 80%, P=0.08). Rates of outpatient follow-up with ID provider were similar between groups (79% vs 81%, P=0.85).
Conclusion: Implementation of OPAT care team service shows a promising decrease in OPAT related re-admission. Implementation of an OPAT care team has the potential to lead to improved clinical success. A study with a larger sample size should be done to confirm these results and draw further conclusions.
Presenting Author
Saipriya Gadiraju PharmDJefferson Health East Region
Authors
Shereef Ali Pharm.D., BCPS, BCCCP
Jefferson Health of New Jersey
Nikunj Vyas PharmD, BCPS
Jefferson Health New Jersey
Alissa Werzen MD
Jefferson Health East Region