Students Research in Progress
Tuesday, October 15, 2024
08:30 AM–10:00 AM
Abstract
Introduction: Diuretics are often used to achieve fluid balance in patients after fluid overload. Protocols for diuretic use tend to focus on regimens for loop diuretics, but few studies have examined protocols for diuretics used in adjunct to loops. Risk factors for receiving an adjunct diuretic have also not been studied to our knowledge.
Research Question or Hypothesis: This study aims to examine the utilization of diuretics in adjunct to loop diuretics and analyze potential risk factors for adjunct diuretic use in the critical care setting.
Study Design: The study is a single-center retrospective cohort study.
Methods: We included patients admitted to the adult medical critical care unit (MICU) at OU Medical Center between December 4, 2023 to April 4, 2024 with administration of furosemide, torsemide, bumetanide, acetazolamide, metolazone, chlorothiazide, tolvaptan or conivaptan, albumin, or hypertonic saline. Data collection points included daily incidence of loop diuretic administration, daily incidence of adjunct diuretics (thiazides, acetazolamide, albumin, SGLT2i, spironolactone) administration, daily fluid balance, and safety endpoints. Variables with a p value <0.05 from bivariate tests will be considered assessment of risk factors in a multivariable, binary logistic regression.
Results: N/A
Conclusion: N/A
Presenting Author
Braydon Moore PharmD StudentUniversity of Oklahoma Health Sciences Center
Authors
Jordan Fuller PharmD, MBA, BCPS, BCCCP
Corey Guidry PharmD, BCPS
University of Oklahoma
Brandon Sheehy PharmD Student