Scientific Poster Session II - Residents and Fellows Research-in-Progress

Residents and Fellows Research in Progress
  Sunday, October 13, 2024
  12:45 PM–02:15 PM

Abstract

Introduction: Current guideline recommendations support initiation and optimization of GDMT for patients with HFrEF (Heart Failure with Reduced Ejection Fraction). Previous literature has shown significant gaps in appropriate prescribing of GDMT due to patient, clinician, and health system barriers. Virginia Commonwealth University Health System (VCUHS) has implemented interventions aimed to standardize HF care as part of a Clinical Variation Reduction Project with a focus on key performance indicators such as order-set utilization, and GDMT for acute hospitalizations.

Research Question or Hypothesis: Since implementation of a HF Clinical Variation Reduction project, what is the current variation of GDMT prescribing practice at VCUHS?

Study Design: This is a retrospective quality improvement project aimed at evaluation of current GDMT prescribing upon discharge.

Methods: Patient identification and data collection will be conducted via the HF Clinical Reduction Dashboard and electronic medical review.

Data Analysis/Statistics: Descriptive statistical analysis will evaluate current prescribing practices. Continuous data will be analyzed via independent t-tests and categorical data will be analyzed via Pearson Chi Squared Test.

Results: The primary outcome assessed will be the percent of patients on optimal medical therapy upon discharge (all recommended first line classes of GDMT for HFrEF or with a documented contraindication). Included secondary outcomes will be the percent of patients discharged on or with documented contraindication for each individual class of GDMT, total 30-day readmission rates, percent order-set utilization, percent of target GDMT achieved, and percent of therapy changes (optimization, addition, reduction, or discontinuation). Comparisons will be made to look at prescribing practices amongst service lines.

Conclusion: The findings of this project will be reviewed with the HF Clinical Reduction Variation Project and cardiology QAPI (Quality Assurance and Performance Improvement) committees.

Presenting Author

Addison Taylor Doctorate of Pharmacy
Virginia Commonwealth University Health System

Authors

Kylie Weigel Doctorate of Pharmacy
Virginia Commonwealth University Health System