American College of Clinical Pharmacy
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Demystifying Estimates of Kidney Function


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Dose-adjusting medications for chronic or acute kidney impairment is critical to maintain efficacy and mitigate the toxicity of many medications. Pharmacists face challenges in choosing best practices for determining kidney function and estimating this appropriately in the setting of acute changes in hemodynamic status. This session will examine updates such as removing race from equations for estimating kidney function and transitioning to the use of eGFR for drug-related decision-making and how these concepts influence patient care. Case-based scenarios will be presented throughout to examine the best ways to dose medications eliminated via the kidneys.

Release Date: November 12, 2025
ACPE Deadline: October 21, 2028

Publication Year: 2025
Format: Recorded Lecture

Technical Requirements:

To access this on-demand content, you will need broadband Internet access, an updated Internet browser, and speakers or headphones for audio.

Contents

Demystifying Estimates of Kidney Function

  • From Nephron to Numbers: Unraveling the Evolution of Kidney Function Estimates
  • eGFR for Drug Dosing - The New Frontier

Demystifying Estimates of Kidney Function

Faculty

Andrew S. Bzowyckyj, Pharm.D., FAPhA, FADCES, BCPS, CDCES
Senior Scientific Director, Learning Consultant
National Kidney Foundation
New York, NY
Tracy Anderson-Haag, Pharm.D., BCPS, BCTXP
Clinical Pharmacy Specialist-Transplantation
Residency Program Director, PGY-2 Solid Organ Transplant
Hennepin Healthcare
Adjunct Associate Professor
University of Minnesota, College of Pharmacy
Minneapolis, MN

CPE Credit

The American College of Clinical Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.

Target Audience: Pharmacists

Contents

Demystifying Estimates of Kidney Function

Activity Number: 0217-0000-25-114-H01-P
Contact Hour(s): 1.50
Activity Type: Application Based
Learning Objectives
  1. Describe the evolution of kidney function estimation equations including rationale for the development of non-race-based estimated glomerular filtration rate (eGFR) equations.
  2. Interpret the rationale, recommendations, and supporting evidence for using non-race-based eGFR equations rather than eCrCl (Cockcroft-Gault (C-G) equation) for drug-related decisions.
  3. Examine various methods for estimating eGFR for drug-related decision-making.
  4. Select the most appropriate eGFR equation for drug dosing depending on the clinical scenario.
  5. Formulate a plan to best implement the change from the Cockcroft-Gault (C-G) eCrCl equation to the CKD-EPI eGFR equations for drug dosing within your pharmacy practice.

Commercial Support

The American College of Clinical Pharmacy does not solicit or accept external commercial/financial support for its continuing pharmacy education activities. No commercial/financial support has been solicited or accepted for this activity.