Module 1A: Guidelines, Consensus Reports, and Policy

This module focuses on recent guidelines, consensus reports and policy publications. Topics include antibiotic prophylaxis in injury, hyperglycemic crisis, hyperemesis syndrome, and hypertension.

Appelbaum RD, Farrell MS, Gelbard RB, et al. Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open. 2024: 9:e001304

• Describe the clinical consensus document from the American Association for the Surgery of Trauma (AAST) Critical Care Committee for the use of antibiotic prophylaxis in patients with traumatic injury
• Develop recommendations for the use of antibiotic prophylaxis in adult trauma patients who are at risk for infection because of their injury

Umpierrez GE, Davis GM, ElSayed NA, et al. Hyperglycemic crises in adults with diabetes: a consensus report. Diabetes Care 2024; 47: 1257 - 1275.

• Describe the multiorganizational consensus report on hyperglycemic crises in adults with diabetes from the American Diabetes Association (ADA), European Association for the Study of Diabetes (EASD), and other groups
• Develop recommendations for the diagnosis, treatment, and prevention of diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) in adults with diabetes mellitus

Borgundvaag B, Bellolio F, Miles I, et al. Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4): Alcohol use disorder and cannabinoid hyperemesis syndrome management in the emergency department. Acad Emerg Med. 2024;31(5):425-455. doi:10.1111/acem.14911

• Describe the fourth Society for Academic Emergency Medicine (SAEM) Guidelines for Reasonable and Appropriate Care in the Emergency Department (GRACE-4) pertaining to alcohol withdrawal syndrome, alcohol use disorder, and cannabinoid hyperemesis syndrome management
• Develop recommendations for the management of alcohol withdrawal syndrome, alcohol use disorder, and cannabinoid hyperemesis syndrome in the emergency department

Bress AP, Anderson TS, Flack JM, et al. The management of elevated blood pressure in the acute care setting: a scientific statement from the American Heart Association. Hypertension 2024; 81(8): e94-106

• Describe the scientific statement from the American Heart Association (AHA) for the management of elevated blood pressure in the acute care setting
• Develop recommendations for the management of elevated blood pressure in patients in the emergency department and inpatients

Module 1B: Clinical Updates and Practice Management

This module includes a variety of therapeutic areas. Topics include analgesia in traumatic pain, antibiotics in pediatric sepsis, intracerebral hemorrhage, and nebulized medications.

Le Cornec C, Le Pottier M, Broch H, et al. Ketamine Compared With Morphine for Out-of-Hospital Analgesia for Patients With Traumatic Pain: A Randomized Clinical Trial. JAMA Netw Open. 2024 Jan 2;7(1):e2352844.

• Describe the Intravenous Subdissociative-Dose Ketamine Versus Morphine for Prehospital Analgesia (KETAMORPH) study by Le Cornec and colleagues
• Develop recommendations for pain relief in adults with out-of-hospital acute traumatic pain

Lane RD, Richardson T, Scott HF, et al. Delays to Antibiotics in the Emergency Department and Risk of Mortality in Children With Sepsis. JAMA Netw Open. 2024;7(6):e2413955.

• Describe the study by Lane and colleagues of the relationship between the timing of antibiotic administration and mortality in pediatric patients with sepsis
• Develop recommendations for the initiation of antibiotic therapy in pediatric patients with sepsis

Sheth KN, Solomon N, Alhanti B, et al. Time to anticoagulation reversal and outcomes after intracerebral hemorrhage. JAMA Neurol. 2024;81(4):363-372

• Describe the cohort study by Sheth and colleagues of time to anticoagulation reversal in patients with intracerebral hemorrhage
• Develop recommendations for optimizing outcomes in patients with anticoagulation-associated

Connolly SJ, Sharma M, Cohen AT, et al. Andexanet for Factor Xa inhibitor-associated acute intracerebral hemorrhage. N Engl J Med 2024; 390: 1745 - 1755.

• Describe the ANNEXA-I study by Connolly and colleagues of andexanet alfa for acute intracerebral hemorrhage
• Develop recommendations for the management of factor Xa inhibitor-associated acute intracerebral hemorrhage

Ruff IM, deHavenon A, Bergman DL, et al. 2024 AHA/ASA performance and quality measures for spontaneous intracerebral hemorrhage: a report from the American Heart Association/American Stroke Association. Stroke 2024; 55: e199-230.

• Describe the 2024 American Heart Association (AHA)/American Stroke Association (ASA) performance and quality measures for acute, spontaneous, nontraumatic intracerebral hemorrhage
• Develop recommendations for performance and quality measures to use in improving the quality of care for patients with acute, spontaneous, nontraumatic intracerebral hemorrhage

Weant KA, Baum RA, Hile GB, et al. Nebulized medications in the emergency department: a narrative review of nontraditional agents. Am J Health-Syst Pharm 2024; 81: 88 - 105.

• Describe nontraditional (novel, noncommercial) aerosolized medications administered by the nebulized route used in the emergency department
• Develop recommendations for the administration of nontraditional (novel, noncommercial) aerosolized medications by the nebulized route in the emergency department