Complex Case: Deep Vein Thrombosis and Metabolic Syndrome

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including deep vein thrombosis, type 2 diabetes mellitus, dyslipidemia, and hypertension.
• Identify resources and treatment options for sexually transmitted infections.
• Select appropriate monitoring considerations of anticoagulation medications.
• Recognize the impact of pharmacogenomic differences on warfarin therapy.

Cardiovascular Disease 

• Interpret signs, symptoms and diagnostic tests in a pediatric patient with congenital heart disease (specifically VSD, ASD, TOF, coarctation of aorta, and hypoplastic left heart) or Kawasaki disease.
• Identify drug-related problems, including drug interactions.
• Develop the most appropriate therapy and monitoring plans based on patient-specific information and the most current guidelines.
• Use PALS to determine appropriate therapy for bradycardia and tachycardia.

Neonatal Sepsis 

• Develop appropriate treatment and monitoring plans for a complex neonatal patient with multiple conditions, including patent ductus arteriosus, apnea of prematurity, early and late onset sepsis, and necrotizing enterocolitis.
• Evaluate the clinical and therapeutic implications of placental transfer of medications.
• Identify age-specific pharmacokinetic differences among neonates, infants, children, and adolescents.
• Apply FDA alerts for adverse drug events and drug-drug interactions into clinical practice.
• Identify characteristics that facilitate transfer of medications into the breast milk.

Pediatric Nutrition 

• Evaluate if nutrition needs of a pediatric patient are being met based on assessment of appropriate growth and development.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with parenteral and enteral nutrition needs.
• Evaluate patients for weight (overweight or obese) based on current guidelines.

Complex Case: Sickle Cell Disease with Vaso-Occlusive Crisis

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including a vaso-occlusive crisis, cellulitis, constipation, and need for immunizations.
• Select most appropriate patient controlled analgesia regimen based on vaso-occlusive crisis severity.
• Apply pharmacodynamic principles when selecting appropriate antibiotic regimens.
• Identify required immunizations for adolescents, including patients with risk factors for vaccine-preventable diseases.

Complex Case: Acute Lymphoblastic Leukemia with Tumor Lysis Syndrome

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including acute lymphoblastic leukemia (ALL), tumor lysis syndrome, febrile neutropenia, invasive aspergillosis infection, and Clostridium difficile infection.
• Select appropriate medication dose modifications related to hepatic impairment.

Select Topics in Pediatric Hematology and Oncology

• Interpret signs, symptoms and diagnostic tests for chemotherapy-induced nausea and vomiting, mucositis, immune thrombocytopenia, infantile hemangioma, and palliative care in pediatric cancer patients.
• Evaluate patient information to identify drug-related problems and response to therapy.
• Identify appropriate modifications and supportive care plans based on patient-specific follow up assessment.

Regulatory and IRB Considerations

• Identify appropriate off-label use of medications in the pediatric population.
• Recognize IRB requirements for documentation of clinical studies.
• List characteristics of patients who require informed assent/consent.
• Recognize federal legislation relevant to the use of medications in pediatric patients.

Complex Case: Acute Asthma

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including acute and chronic asthma, ADHD, acne, and GERD.
• Evaluate essential components of social history, including smoke exposure and home environment.
• Formulate a plan to address barriers to patient education and adherence, including age, language, cultural considerations, and inhaler technique
• Describe the impact of age on classification and management of asthma.
• Assess available resources to improve access to medications, including patient assistance programs.

Select Topics in Pediatric Pulmonary Disease

• Interpret relevant clinical and laboratory data and results of diagnostic procedures in a pediatric patient with an exacerbation of cystic fibrosis or chronic asthma.
• Identify relevant differences in laboratory sampling for pediatric patients (e.g., blood volume; method, frequency and timing of sampling).
• Develop the most appropriate therapy and monitoring plans based on patient-specific information and the most current guidelines.

Complex Case: Status Epilepticus and Cardiopulmonary Resuscitation

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions and needs, including status epilepticus, cardiopulmonary resuscitation, and sedation/analgesia.
• Differentiate treatment options in cardiopulmonary arrest based upon patient presentation.
• Select the appropriate dose and route of administration for medications.
• Assess the need and processes for reporting adverse drug events.
• Identify cultural considerations related to treatment and counseling of the pediatric population.
• Distinguish between the four preceptor roles.

Select Topics in Pediatric Critical and Emergency Care

• Interpret diagnostic and/or laboratory tests, vital signs, and clinical presentation of a pediatric patient with traumatic brain injury or select toxicological emergencies (e.g., acetaminophen, ethylene glycol).
• Develop the most appropriate therapy and monitoring plans based on patient-specific information and the most current guidelines.
• Develop appropriate medication dosing plans for a pediatric patient on ECMO.
• Develop plans to manage underlying disorders.

Select Topics in Pediatric Neurology and Psychiatry, Part 1

• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with migraines, autism, cerebral palsy, depression or anxiety.
• Evaluate patients for drug-related problems and response to therapy.
• Identify appropriate modifications of patient-specific treatment plans based on follow up assessment.

Select Topics in Pediatric Neurology - Part 2, Focus on Seizures

• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with febrile seizures, neonatal seizures, infantile spasms, absence seizures, and Lennox-Gastaut syndrome.
• Evaluate patients for drug-related problems.
• Identify appropriate modifications of patient-specific treatment plans based on follow up assessment.

Statistics, Evidence-Based Medicine and Research Design

• Evaluate quality and appropriateness, with specific attention to study design, statistical analysis, internal/external validity, source of bias/confounders, and quality of conclusions and interpretation of graphs.
• Explain why a statistical test is appropriate or not appropriate, based on the sample distribution, data type, and study design.
• Interpret clinical and statistical significance for results from commonly used statistical tests.
• Explain the strengths and limitations of different types of measures of central tendency (mean, median, and mode) and data spread (standard deviation, standard error of the mean, range, and interquartile range).
• Evaluate odds ratio, risk/incidence rate, relative risk, number needed to treat, number needed to harm, and other risk estimates.
• Assess whether the study applies to a specified patient population.

Complex Case: Diabetic Ketoacidosis

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including diabetic ketoacidosis, type 1 diabetes mellitus, and urinary tract infection.
• Calculate maintenance and deficit fluid requirements and urine output.
• Identify factors affecting medication adherence.
• Recommend appropriate dosing of insulin based on patient age and weight.
• Select an effective method of delivery for insulin.

Complex Case: Pneumonia and Septic Shock

• Develop appropriate treatment and monitoring plans for a complex pediatric patient with multiple conditions, including pneumonia, septic shock, and acute kidney injury.
• Calculate creatinine clearance, fluid requirements, and urine output in pediatric patients.
• Apply scoring systems to assess pediatric patients.
• Select appropriate dosing for medications based on renal dysfunction and/or replacement modalities.
• Differentiate vital signs between stable and critically-ill pediatric patients.

Select Topics in Pediatric Infectious Diseases - Part 1

• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a well-appearing febrile infant.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with otitis media.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with bronchiolitis.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with tuberculosis.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with meningitis.
• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with pneumonia.

Select Topics in Pediatric Infectious Diseases - Part 2

• Develop treatment and monitoring plans based on patient-specific information and the most current guidelines for a pediatric patient with HIV, Herpes Simplex Virus Types 1 and 2, or systemic fungal infections.  

Complex Case: Medication Error & Practice Management